Chance and Necessity

If you free-associate the word “chance,” you may arrive at “I’ll take my chances” before potentially arriving at Thomas Bayes’ “Doctrine of Chances”. Jacques Monod was an early explorer of the collision of probability and chance in biology.

THE PRINCE OF CHANCE

Jacques Monod grew up just down the coast from Monte Carlo in Cannes, France, another town famous for its casinos and, later, its film festival. Graced with movie star looks—one prominent French journalist described him as a “prince” who resembled Hollywood icon Henry Fonda, as well as considerable musical talent, and an exceptional intellect, Monod struggled to decide on a career path through his twenties. After distinguishing himself in the French Resistance, Monod rose to fame not as an actor or musician, but as a brilliant biologist. He shared the 1965 Nobel Prize in Physiology or Medicine for seminal discoveries about how genes work.

A pioneer in the field of molecular biology, Monod was privy to the blizzard of discoveries in the 1950s and early 1960s about the molecules that determined the characteristics of living things—what Monod and others dubbed “the secrets of life.” He kept close company with a relatively small international community of leading researchers. For example, when James Watson and Francis Crick cracked the structure of DNA (deoxyribonucleic acid) in 1953, Monod was one of the first with whom Watson shared the breakthrough.

But as a Frenchman steeped in his culture’s deep philosophical traditions, Monod was interested in science for more than just science’s sake. After the war, Monod befriended France’s leading philosopher-writer Albert Camus, and the two men pondered questions of human existence in Left Bank cafés. Monod felt that the public misunderstood the principal purpose of science as being the creation of technology. Rather, Monod believed technology was merely a by-product. He said, “the most important results of science have been to change the relationship of man to the universe, or the way he sees himself in the universe”—a relationship of equally intense interest to his friend Camus.

Monod thought that there were profound philosophical implications of the new molecular biology, particularly in the realm of heredity, which had gone largely unnoted in the broader culture. Several years after his Nobel Prize and Camus’ untimely death, he decided to write a book to try to bring the meaning of modern biology to laypersons.

“[T]he ‘secret of life’…has been laid bare,” he wrote.

“This, a considerable event, ought certainly to make itself strongly felt in contemporary thinking.”

Monod used several chapters to describe the insights that had very recently emerged from the study of DNA and the deciphering of the genetic code. He understood this knowledge would be unfamiliar to most readers, so he included an appendix with chemical structures of proteins and nucleic acids, and a primer on how the genetic code worked.

In a matter-of-fact style, he explained genetic mutations as accidental alterations—substitutions, additions, deletions, or rearrangements—in the text of DNA, in the sequence of the long strings of chemical bases (ACTTGATAA, etc.) that make up genes.

Then, almost without warning, he turned to the broader implications of how mutations arise in DNA. It is worth quoting him at length for after 111 pages of background, he delivered one of the most powerful ideas in five centuries of science (all italics are original):

“We call these events accidental; we say they are random occurrences. And since they constitute the only possible source of modifications in the genetic text, itself the sole repository of the organism’s hereditary structure, it necessarily follows that chance alone is at the source of every innovation, of all creation in the biosphere.

“Pure chance, absolutely free but blind, at the very root of the stupendous edifice of evolution: this central concept of modern biology is no longer one among other possible or even conceivable hypotheses. It is today the sole conceivable hypothesis, the only one that squares with observed and tested fact. And nothing warrants the supposition—or the hope—that on this score our position is likely ever to be revised.

“There is no scientific concept, in any of the sciences, more destructive of anthropocentrism than this one.”

In essence, heretofore obscure discoveries in biochemistry and genetics (largely studied at that time in simple bacteria) had upended two millennia of philosophy and religion that put humans at the center or apex of creation. “Man was the product of an incalculable number of fortuitous events,” Monod wrote. “The result of a huge Monte Carlo game, where our number eventually did come out, when it might not well have appeared.”

Le Hasard et la nécessité (Chance and Necessity) appeared in France in October 1970. It was a fairly technical book with several chapters on philosophy and genetics, and those appendices full of chemical diagrams. A first-time author, Monod did not know what reactions to expect.

The merde hit the fan.

The book received dozens of reviews across France and quickly became a bestseller—second only to the French translation of Erich Segal’s Love Story (this was France after all. After it was translated into English, reviews and interviews with Monod were featured in several of the most prominent British and American newspapers and magazines.

Many commentators immediately recognized the threat chance posed to traditional ideas of humanity’s origins and purpose. To Arthur Peacocke, a British biochemist turned prominent theologian, Monod had put forth “one of the strongest and most influential attacks of the century on theism.” A flurry of articles and books appeared with titles such as Anti-Chance: A Reply to Monod’s Chance and Necessity, Beyond Chance and Necessity, and God, Chance, and Necessity. Monod was invited to debate philosophers and theologians both in France and abroad, on television, radio, and in print.

American Calvinist theologian and pastor R.C. Sproul summed up the high stakes posed by chance in the first page of his book Not A Chance:

“It is not necessary for chance to rule in order to supplant God. Indeed, chance requires little authority at all if it is to depose God; all it needs to do the job is to exist. The mere existence of chance is enough to rip God from his cosmic throne. Chance does not need to rule; it does not need to be sovereign. If it exists as a mere impotent, humble servant, it leaves God not only out of date, but out of a job.” More than two hundred pages later, Sproul concluded:

“Chance as a real force is a myth. It has no basis in reality and no place in scientific inquiry. For science and philosophy to continue to advance in knowledge, chance must be demythologized once and for all.”

Sproul and other critics argued that what scientists perceived as chance merely reflected a lack of knowledge of true causes. Perhaps that was the expression of hope to which Monod alluded—the hope that as scientists learned more, our position on the role of chance would somehow be revised.

A SECOND CHANCE

The ensuing fifty years have not played out as either Monod or his detractors hoped. The Frenchman thought that the new insights from molecular biology should be a turning point for modern society-away from traditional beliefs about causes in the natural world toward one that embraced randomness and our chance existence.

Ha! Fat chance. The excitement and fuss stirred by Chance and Necessity simmered down, and Monod passed away a few years later. Surveys reveal that the majority of Americans, for example, continue to believe that everything on earth happens for His reasons.

But Monod’s critics should take no comfort. The province of chance in the biosphere and human life has been revised, although not at all in the scope or direction that they hoped.

The domain of chance has expanded into realms neither Monod nor anyone else imagined.

As we have learned much more about the history and workings of the planet, we have been startled to discover how the course of life has been buffeted by a variety of cosmological and geological accidents—without which we would not be here. As we have explored human history, we have seen how pandemics, droughts, and other civilization-changing episodes have been triggered by random, singular events in nature that easily might not have happened. And as we have probed human biology and the factors that impact our individual lives, we have caught chance red-handed, reigning over the often-thin line between life and death.

This book tells the stories that Monod could not—of astonishing discoveries from the planetary to the molecular scale, from great upheavals across the globe to the machinery of chance that operates within every cell of every creature, including ourselves. And while these discoveries vaporize the comforts of anthropocentrism, the story of chance, I hope you will come to agree, is much more than highfalutin philosophy or the refutation of theologians’ wishful thinking.

I hope that you are awed—awed by the power and the drama of asteroids slamming into the planet, of continents colliding, and of the rapid rising and falling of ice and oceans; awed by the realization that we live on (and are at the mercy of a planet that is far more unstable than our short lives perceive; awed by the knowledge of how random chance is at the source of all of the beautiful and wondrous creatures with whom we share the planet; awed by the unique invisible accidents that made each one of us; and awed by the fact that we humans, recent descendants of bands of hunter-gatherers who persevered through a period of exceptional chaos, have in just the last fifty years or so, figured all of this out!

My goal here is to be comprehensible without being comprehensive. It is almost trivial to claim that the world is the way it is or that we are here because of a long chain of chance, albeit fortunate, events. The explanatory power I seek comes from specificity. It is essential to unpack some of those events to appreciate how they shape the direction of life. The layout of the book follows a simple three-part logic. I’ll begin with inanimate, external chance events that have shaped the conditions for life (Part One, “Stuff Happens”), and then turn to the internal random mechanism within every creature that generates the adaptations to those conditions (Part Two, “A World of Mistakes”). Then, I bring the story to the personal level (Part Three, “23 and You”) and how chance impacts our natural lives, as well as our deaths. Our chance-driven existence shatters long-held beliefs about humanity’s place and raises challenging questions about the meaning and purpose of our lives. In the Afterword, I’ll offer some possible replies with the help of some special guests.

This is a relatively small book for a really big idea. Science has given us a handful of really big ideas over the centuries, but they have been received in funny ways. Darwin had a huge idea that was very simple to understand, and even though the evidence is massive and everywhere, many refuse to believe it. Einstein had a brand new idea, and even though few understand it or the evidence for it, most everyone seems to believe it. Monod had a great idea, but these days most people (other than scholars) have not heard of it, or of him.

My greatest hope, then, is that this short book might be chance’s second chance.

Sean B. Carroll, A Series of Fortunate Events: Chance and the Making of the Planet, Life, and You, Princeton University Press, 2020, pp. 6-12.

Modern biology as described by Monod pushes the linkage of probability, randomness and chance to the center. At the time, this was a very radical and profound way of looking at biology. If we combine Monod’s biology with theoretical physics like Lawrence KraussA Universe from Nothing: Why There Is Something Rather than Nothing, we realize that accidentality is the bedrock on which our knowledge of the universe is built.

Can a Movie Excite an Unexpected Intellectual Adventure?

Consider the political thriller The Eagle Has Landed. There’s a scene where Col. Radl discusses Jung’s concept of synchronicity. For example, a man checking out drops a coin near the register and searches for it momentarily before giving up. Years later, he is at the same store and finds a similar coin. He rationalizes this with a mundane story, not some cosmic notion of fairness.

Jung was working, in collaboration with Pauli, on his treatise on Synchronicity: An Acausal Connecting Principle, which was published together with Pauli’s essay on Kepler in one volume. This was evidently meant as a symbolic act: one of the greatest physicists of the century joining forces with one of its greatest psychologists. The result was a stimulating exercise in unorthodox speculation, but at the same time sadly disappointing. It did not amount to a theory in the proper sense, but rather to a universal schema, both very bold and very vague.

Jung’s treatise hinges on his concept of “Synchronicity”. He defines it as “the simultaneous occurrence of two meaningfully but not causally connected events”;1 or alternatively as “a coincidence in time of two or more causally unrelated events which have the same or similar meaning2…equal in rank to causality as a principle of explanation”.3 This is an almost verbatim repetition of Kammerer’s definition of “Seriality” as “a recurrence of the same or similar things or events in time or space”—events which, as far as can be ascertained; “are not connected by the same acting cause”. The main difference appears to be that Kammerer emphasises serial happenings in time (though, of course, he includes contemporaneous coincidences in space), whereas Jung’s concept of synchronicity seems to refer only to simultaneous events—although he includes precognitive dreams which occurred sometimes several days before the events. He tried to get around the time paradox by saying that the unconscious mind functions outside of the physical framework of space-time; thus precognitive experiences are “evidently not synchronous but are synchronistic since they are experienced as psychic images in the present as though the objective event already existed”.4 One wonders why Jung created these unnecessary complications by coining a term which implies simultaneity, and then explaining that it does not mean what it means. But this kind of obscurity combined with verbosity runs through much of Jung’s writing.

Although Kammerer’s “Seriality” and Jung’s “Synchronicity” are as similar as a pair of gloves, each fits one hand only. Kammerer confined himself to analogies in naive physical terms, rejecting ESP and mentalistic explanations. Jung went to the opposite extreme and tried to explain all phenomena which could not be accounted for in terms of physical causality, as manifestations of the unconscious mind: “Synchronicity is a phenomenon that seems to be primarily connected with psychic conditions, that is to say with processes in the unconscious.”5 Its deepest strata, according to Jungian terminology, are formed by the “collective unconscious”, potentially shared by all members of the race. The “decisive factors” in the collective unconscious are the archetypes which “constitute its structure”.6 They are, as it were, the distilled memories of the human species, but cannot be represented in verbal terms, only in elusive symbols, shared by all mythologies. They also provide “patterns of behaviour”7 for all human beings in archetypal situations—confrontations with death, danger, love, conflict, etc. In such situations the unconscious archetypes invade consciousness, carrying strong emotions and—owing perhaps to the archetype’s indifference to physical space and time—facilitate the occurrence of “synchronistic” events. The appearance of the scarab while the patient was telling her archetypal dream is considered by Jung as an illustration of this nexus. The same applies to the detonations in Freud’s bookcase during Jung’s visit, indicating the explosive nature of their father-son relationship: “Meaningful coincidences which are to be distinguished from meaningless chance-groupings—therefore seem to rest on an archetypal foundation. At least all the cases in my experience and there is a large number of them—show this characteristic?”8

Elsewhere in the essay he writes:

Synchronistic events rest on the simultaneous occurrence of two different psychic states. One of them is the normal, probable state (i.e., the one that is causally explicable), and the other, the critical experience, is the one that cannot be derived causally from the first. In the case of sudden death, the critical experience cannot be recognised immediately as “extra-sensory perception” but can only be verified as such afterwards. …In all these cases, whether it is a question of spatial or of temporal ESP, we find a simultaneity of the normal or ordinary state with another state or experience which is not causally derivable from it, and whose objective existence can only be verified afterwards. …An unexpected [mental] content which is directly or indirectly connected with some objective external event coincides with the ordinary psychic state: this is what I call synchronicity.”9

  1. Jung (1960), p. 441 [ref]
  2. Jung (1960), p.551 [ref]
  3. Jung (1960), p. 435 [ref]
  4. Jung (1960), p. 445 [ref]
  5. Jung (1960), p. 511 [ref]
  6. Jung (1960), p. 436 [ref]
  7. Jung (1960), p. 438 [ref]
  8. Jung (1960), p. 440 [ref]
  9. Jung (1960), pp. 444-5 [ref]
Arthur Koestler, The Roots of Coincidence, Picador, 1974 (first published by Hutchinson & Co. Ltd., 1972), pgs. 94-97.

Can a movie trigger an unexpected intellectual adventure?

Usually, when considering this question, you might see a film on a specific subject, then perhaps read an article or try to find a book about it.

In his essay on Synchronicity (Jung’s term for meaningful coincidences of events separated in space and/or in time,1 Jung examined some of the beliefs surrounding apparently related incidents which seem to have no causal connection. These incidents could be, for example, the coinciding of a patient’s dream with an actual event corresponding to its occurring at the same time some distance away, it could be ESP phenomena—response to some event that does not become known through any sense; it could be a horoscope reading which corresponds to the observed character of the individual or his self-image, or an astrological prediction which seems to be borne out in subsequent events. The possibility of finding meaning in these correspondences had tantalized Jung for many years. The beginning of his serious study goes back to the days when Albert Einstein was developing his first theory of relativity. During this time he was a guest on several occasions for dinner in Jung’s home. In a letter on Einstein and synchronicity, Jung wrote: “It was Einstein who first started me off thinking about a possible relativity of time as well as space, and their psychic synchronicity.”2

  1. In The Structure and Dynamics of the Psyche, C. W. 8, pp. 417-531. [ref]
  2. Letter to Dr. Selig dated 25 February, 1953, in Spring, 1971, p. 127. [ref]
June Singer, Boundaries of the Soul: The Practice of Jung’s Psychology, Anchor Books edition, 1973, p. 398.

The Eagle Has Landed begins with newsreel footage depicting Mussolini’s rescue by the Germans during the Gran Sasso raid. This probably inspires the plot to abduct Churchill. Come to the present. Did the operation to capture Venezuelan president Nicolás Maduro and his wife, Cilia Flores, stem from this, or is there no causal connection? All of this is the intellectual adventure of Jung’s synchronicity.

Signs and Meanings: Education and Semiotics

One learns to function in a world of posters, postings, signs, ads, ordinances, notices and indications of “material culture” (i.e. commerce expressed in designs and slogans on walls and buses, subway cars, etc.).

Think of the 1963 movie The Great Escape. There’s a scene where James Coburn’s Australian character is sitting in an outdoor cafe on the French/Spanish border and the waiter comes over to him and pulls him toward the counter and says, “Telephon, monsieur.”

The James Coburn character has no idea why this is happening but mimics the proprietor and son when they duck down. French Resistance fighters in a car gun down the Germans at the cafe and James Coburn’s character “gets it” and asks them for help to get into Spain. As he ducks down you see posted on the wall of the cafe several ad signs for drinks. One of them is “Byrrh”:

Byrrh is an aromatised wine-based apéritif made of red wine, mistelle, and quinine. Created in 1866 and a trademark since 1873, it was popular as a French apéritif. With its marketing and reputation as a ‘hygienic drink,’ Byrrh sold well in the early 20th century.” (from Wikipedia)

In many French movies or movies set in France, such as Belle de Jour and The Legend of the Holy Drinker from 1988 (in which a drunken homeless man [played by Rutger Hauer] in Paris is lent 200 francs by a stranger as long as he promises to repay it to a local church when he can afford to; the film depicts the man’s constant frustrations as he attempts to do so).

Byrrh” appears routinely and a French child begins to ‘get the picture’ on what is being signified and how it differs from other notices, commercial or legal or municipal.

Set in Paris, the ad notice “Byrrh” appears in the same way you’d expect to see “Coca-Cola” and know what the sign signifies. “Coke” is a drink and not the fuel coke. How exactly you make these distinctions is unclear to linguists and other language-watchers. It’s a social phenomenon, partly, like mores and manners.

In the movie The Book Thief (a 2013 World War II war drama, starring Geoffrey Rush, Emily Watson, and Sophie Nélisse, based on the 2005 novel) there’s a moment when you see a sign advertising or reminding you of “Kolonialwaren” (i.e., colonial wares) which was the German way of pointing to a place or store that sold coffee, tea, cocoa, etc. Any German adult of the period would know what “Kolonialwaren” signifies without quite knowing how he or she knows.

A traffic sign (you have to of course realize it’s a traffic sign and not some commercial ad) tells you “Boston 20 m.” You realize or guess it means 20 miles and not 20 meters (since meters are not a typical American measure) nor would it be 20 minutes since that would assume everyone is driving at a speed that gives you 20 minutes, which is far-fetched.

How a person goes from birth to adulthood whereby they spontaneously navigate a welter of different signs and postings, ads and statutes is quite opaque.

Roland Barthes (died 1980) explored this domain of signs (not only physical signs but mythology as a system of signs) all his life:

Barthes is one of the leading theorists of semiotics, the study of signs. A sign, in this context, refers to something which conveys meaning – for example, a written or spoken word, a symbol or a myth.

Education should not ignore “material culture” (i.e., the history of things) and semiotics (i.e., the world “speaking” to you via designs and signs and words).